SCHEMBL6422082

SCHEMBL6422082

C=C(C)C(=O)Nc1cc(S(N)(=O)=O)cc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.49
CA9 Q16790 10/20 0.49
CA1 P00915 9/20 0.49
CA12 O43570 6/20 0.49
POLB P06746 2/20 0.45
CYP1A2 P05177 1/20 0.45
CASP6 P55212 1/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 1/20 0.40
ACP1 P24666 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.38
CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6847926 0.80 CA2 (0.50) CA2CA9CA1CA12POLB
SCHEMBL10040374 0.79 CDC25B (0.50) POLBKDM4ENPC1RAB9AACP1
SCHEMBL13588248 0.79 RAB9A (0.45) POLBCYP1A2KDM4ENPC1RAB9A
SCHEMBL13609731 0.79 ALDH1A1 (0.53) POLBCYP1A2KDM4ENPC1RAB9A
SCHEMBL10626847 0.76 CASP6 (0.76) CA2CA9CA1CA12POLB
SCHEMBL194202 0.75 RAB9A (0.61) POLBCYP1A2KDM4ENPC1RAB9A
SCHEMBL30369173 0.75 RAB9A (0.61) POLBCYP1A2KDM4ENPC1RAB9A
SCHEMBL397324 0.75 MEN1 (0.42) CA2CA9CA1CA12POLB
SCHEMBL9885826 0.74 LDHA (0.49) CA2CA9CA1CA12KMT2A
SCHEMBL15782654 0.73 TDP1 (0.49) POLBCYP1A2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6844138-B2 Heat sensitive element FUJI PHOTO FILM CO., LTD. (JP) 2005-01-18 US disclosed
US-6806031-B2 AN ALUMINUM PLATE IS SUBJECTED TO GRAINING, ALKALI ETCHING AND ANODIZING, A PHOTOSENSITIVE LAYER BECOMES ALKALI-SOLUBLE BY PHOTOTHERMAL CONVERSION WITH LASER BEAMS FUJI PHOTO FILM CO., LTD. (JP) 2004-10-19 US disclosed
US-20020142250-A1 Heat sensitive element FUJIFILM CORPORATION (JP) 2002-10-03 US disclosed
US-6455222-B1 PRECURSOR COMPRISING SUBSTRATE HAVING IMAGE RECORDING LAYER CONTAINING FINE LIGHT-HEAT CONVERTIBLE PARTICLES COATED WITH HYDROPHILIC MATERIAL, WHICH CAN BE MADE HYDROPHOBIC BY HEATING FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020094490-A1 An aluminum plate is subjected to graining, alkali etching and anodizing, a photosensitive layer becomes alkali-soluble by photothermal conversion with laser beams FUJIFILM CORPORATION (JP) 2002-07-18 US disclosed