Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | PRKACG | P22612 | 2/20 | 0.31 |
| ▸ | PRKACB | P22694 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425919 | 0.98 | HSD11B1 (0.35) | HSD11B1MEN1KMT2AMGLLFAAH | |
| SCHEMBL6464934 | 0.92 | PDE2A (0.35) | HSD11B1MGLLFAAHPDE2AAKR1C3 | |
| SCHEMBL6423924 | 0.92 | AKR1C3 (0.41) | MEN1KMT2AMGLLAKR1C3AKR1C2 | |
| SCHEMBL6453005 | 0.90 | PDE2A (0.35) | MGLLFAAHPDE2AAKR1C3AKR1C2 | |
| SCHEMBL6424976 | 0.90 | HSD11B1 (0.36) | HSD11B1MGLLFAAHTAS1R3TAS1R2 | |
| SCHEMBL6425630 | 0.90 | AKR1C3 (0.41) | MEN1KMT2AMGLLAKR1C3AKR1C2 | |
| SCHEMBL6423665 | 0.89 | ALDH1A1 (0.37) | HSD11B1MEN1KMT2AMGLLAKR1C3 | |
| SCHEMBL6424870 | 0.89 | TDP1 (0.38) | HSD11B1MEN1KMT2AMGLLGRM5 | |
| SCHEMBL6424954 | 0.89 | PTGS2 (0.42) | HSD11B1MEN1KMT2AMGLLTAS1R3 | |
| SCHEMBL6424784 | 0.88 | HSD11B1 (0.36) | HSD11B1MGLLFAAHAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | HSD11B1 1120/4885MEN1 3824/4885KMT2A 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.