Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 6/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425599 | 0.98 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1HSD11B1KDM4ECNR1 | |
| SCHEMBL6423571 | 0.91 | USP2 (0.39) | ALDH1A1HSD11B1KDM4EGRM5MEN1 | |
| SCHEMBL6426725 | 0.89 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1HSD11B1KDM4EGRM5 | |
| SCHEMBL6426581 | 0.89 | TDP1 (0.41) | ALDH1A1HSD11B1KDM4EMEN1KMT2A | |
| SCHEMBL6425922 | 0.89 | AKR1C3 (0.40) | KDM4EMEN1KMT2AMGLLSLC6A3 | |
| SCHEMBL6426891 | 0.88 | HSD11B1 (0.37) | ALDH1A1HSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6424426 | 0.88 | KMT2A (0.36) | ALDH1A1HSD11B1GRM5MEN1KMT2A | |
| SCHEMBL6426945 | 0.88 | PDE2A (0.35) | HSD11B1MGLL | |
| SCHEMBL6425475 | 0.88 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1HSD11B1KDM4ECNR1 | |
| SCHEMBL6422936 | 0.87 | AKR1C3 (0.40) | ALDH1A1KDM4EMEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | ALDH1A1 630/4885L3MBTL1 4595/4885HSD11B1 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.