Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426701 | 0.94 | PSIP1 (0.33) | PSIP1KDM4EALDH1A1 | |
| SCHEMBL6424213 | 0.92 | AKR1C3 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL6425699 | 0.90 | AKR1C3 (0.37) | PSIP1 | |
| SCHEMBL5560478 | 0.88 | PSIP1 (0.36) | PSIP1KDM4EALDH1A1SLC6A3SLC6A2 | |
| SCHEMBL6423140 | 0.88 | TAS1R3 (0.38) | PSIP1 | |
| SCHEMBL6424330 | 0.86 | PTGS2 (0.34) | — | |
| SCHEMBL6425777 | 0.84 | AKR1C3 (0.36) | PSIP1 | |
| SCHEMBL6423408 | 0.84 | AKR1C3 (0.40) | ALDH1A1SLC6A3SLC6A2 | |
| SCHEMBL6425587 | 0.83 | CA1 (0.30) | — | |
| SCHEMBL6423242 | 0.83 | CA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | PSIP1 2842/4885KDM4E 2209/4885ALDH1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.