Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153824 | 1.00 | TRPA1 (0.43) | TRPA1CYP1A2CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6154333 | 1.00 | TRPA1 (0.43) | TRPA1CYP1A2CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6154294 | 0.84 | MME (0.41) | MEN1KMT2APPARGPPARA | |
| SCHEMBL11081780 | 0.83 | PIN1 (0.41) | TRPA1CYP1A2MEN1KMT2ASRR | |
| SCHEMBL6153593 | 0.82 | ALDH1A1 (0.46) | CYP1A2ALDH1A1MMP8MEN1KMT2A | |
| SCHEMBL6154318 | 0.82 | ALDH1A1 (0.46) | CYP1A2ALDH1A1MMP8MEN1KMT2A | |
| SCHEMBL6154154 | 0.82 | ALDH1A1 (0.46) | CYP1A2ALDH1A1MMP8MEN1KMT2A | |
| SCHEMBL6153740 | 0.80 | GAA (0.44) | CYP1A2CYP3A4ALDH1A1PPARGPPARA | |
| SCHEMBL4756128 | 0.80 | CA1 (0.40) | CYP1A2MEN1KMT2ASRR | |
| SCHEMBL4756135 | 0.80 | CA1 (0.40) | CYP1A2MEN1KMT2ASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143593-A1 | Process for producing 2-aralkylpropionic acid derivative | KANEKA CORPORATION (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1466895-A1 | PROCESS FOR PRODUCING 2-ARALKYLPROPIONIC ACID DERIVATIVE | KANEKA CORPORATION (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143593-A1 | Process for producing 2-aralkylpropionic acid derivative | AASDHPPT, ADSL, HACL2 | TRPA1 828/4885CYP1A2 1178/4885CYP3A4 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.