Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 8/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423536 | 0.98 | HSD11B1 (0.38) | HSD11B1MGLLPPARGEPHX2PDE4B | |
| SCHEMBL6423593 | 0.88 | HSD11B1 (0.39) | HSD11B1MGLLPPARGEPHX2PDE4B | |
| SCHEMBL6423869 | 0.88 | AKR1C3 (0.39) | PTGS2 | |
| SCHEMBL5798044 | 0.88 | AKR1C3 (0.37) | PPARGPTGS2 | |
| SCHEMBL6423817 | 0.86 | HSD11B1 (0.39) | HSD11B1MGLLPPARGEPHX2PPARA | |
| SCHEMBL6425845 | 0.86 | PTGS2 (0.38) | PPARGPPARAHRH3PTGS2 | |
| SCHEMBL6427372 | 0.86 | MEN1 (0.36) | HSD11B1MGLL | |
| SCHEMBL6423103 | 0.86 | AKR1C3 (0.39) | MGLLPPARGPTGS2 | |
| SCHEMBL6424855 | 0.85 | PPARG (0.39) | HSD11B1PPARGEPHX2PDE4BPDE4D | |
| SCHEMBL6423768 | 0.85 | PPARG (0.40) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | HSD11B1 1120/4885MGLL 108/4885PPARG 1908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.