Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625231 | 0.81 | ALOX15 (0.36) | NPC1RAB9AKMT2AMEN1HPGD | |
| SCHEMBL28559658 | 0.80 | KDM4E (0.34) | KMT2AMEN1 | |
| SCHEMBL28847404 | 0.80 | HTT (0.34) | — | |
| SCHEMBL18209664 | 0.77 | POLB (0.37) | — | |
| SCHEMBL6065184 | 0.76 | TSHR (0.33) | NPC1 | |
| SCHEMBL1831743 | 0.74 | ALDH1A1 (0.31) | KMT2AMEN1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19313103 | 0.74 | — | — | |
| SCHEMBL18209671 | 0.73 | ALOX5 (0.33) | — | |
| SCHEMBL1456373 | 0.73 | RAB9A (0.56) | NPC1RAB9AKMT2ARIPK2HPGD | |
| Hydrochloric Acid SCHEMBL29907682 | 0.72 | GAA (0.36) | KMT2AMEN1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |