Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425225 | 0.91 | AKR1C3 (0.38) | ALDH1A1KMT2AAKR1C3AKR1C2NOTUM | |
| SCHEMBL6426839 | 0.89 | MEN1 (0.34) | MEN1KMT2ASLC6A2AKR1C3AKR1C2 | |
| SCHEMBL6424132 | 0.89 | AKR1C3 (0.41) | MEN1KMT2AAKR1C3AKR1C2SLC6A3 | |
| SCHEMBL6423708 | 0.89 | AKR1C3 (0.35) | ALDH1A1L3MBTL1MEN1KMT2ASLC6A2 | |
| SCHEMBL5560505 | 0.87 | RORC (0.33) | AKR1C3AKR1C2 | |
| SCHEMBL6423787 | 0.87 | AKR1C3 (0.32) | ALDH1A1AKR1C3AKR1C2NOTUM | |
| SCHEMBL6423752 | 0.87 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MEN1KMT2ASLC6A2 | |
| SCHEMBL5560366 | 0.87 | PTGS2 (0.39) | ALDH1A1L3MBTL1MEN1KMT2ASLC6A2 | |
| SCHEMBL5551752 | 0.87 | PTGS2 (0.39) | ALDH1A1L3MBTL1MEN1KMT2ASLC6A2 | |
| SCHEMBL5559382 | 0.87 | PTGS2 (0.39) | ALDH1A1L3MBTL1MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | ALDH1A1 630/4885L3MBTL1 4595/4885MEN1 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.