Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | ADH5 | P11766 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735868 | 0.85 | ADH5 (0.38) | DHODHADH5 | |
| SCHEMBL5735900 | 0.79 | FFAR1 (0.40) | TBXAS1FFAR1 | |
| SCHEMBL6427800 | 0.78 | TDP1 (0.36) | ALDH1A1FFAR1AAK1 | |
| SCHEMBL7984336 | 0.74 | PDE4A (0.37) | TBXAS1DHODHHCRTR1HCRTR2PDE4A | |
| SCHEMBL6427151 | 0.73 | TBXAS1 (0.46) | TBXAS1CYP19A1 | |
| SCHEMBL5735726 | 0.70 | ADH5 (0.47) | TBXAS1ADH5ALDH1A1 | |
| SCHEMBL6427628 | 0.69 | TDP1 (0.38) | ALDH1A1CYP19A1FFAR1AAK1 | |
| SCHEMBL5736507 | 0.67 | FFAR1 (0.44) | TBXAS1FFAR1 | |
| SCHEMBL5738924 | 0.66 | LMNA (0.49) | TBXAS1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7980582 | 0.65 | IDO1 (0.49) | TBXAS1DHODHADH5ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855512-B2 | Methods for identifying inhibitors of cytochrome P450RAI | ALLERGAN, INC. (US) | 2005-02-15 | — | — | US | disclosed |
| US-6369261-B1 | CYCLOPROPYLBENZENE DERIVATIVE OF ACIDS OR ESTERS | ALLERGAN SALES, INC. | 2002-04-09 | — | — | US | disclosed |
| US-6369225-B1 | ENZYME INHIBITORS | ALLERGAN SALES, INC. | 2002-04-09 | — | — | US | disclosed |
| US-6303785-B1 | SUBSTITUTED N-CYCLOPROPYLTETRAHYDROISOQUINOLINES | ALLERGAN SALES, INC. | 2001-10-16 | — | — | US | disclosed |