Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439273 | 0.79 | LMNA (0.58) | ALDH1A1HPGDGLAKDM4EPOLB | |
| SCHEMBL30777218 | 0.76 | BCHE (0.54) | BCHEACHEALDH1A1HPGDGLA | |
| SCHEMBL6535800 | 0.75 | ALDH1A1 (0.64) | ALDH1A1PKMKDM4EPOLBL3MBTL1 | |
| SCHEMBL8526862 | 0.75 | P2RX4 (0.55) | ALDH1A1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL5918694 | 0.75 | KMT2A (0.62) | ALDH1A1PKMKDM4EPOLBL3MBTL1 | |
| SCHEMBL11714079 | 0.74 | KMT2A (0.57) | BCHEACHEALDH1A1CASP3CASP7 | |
| SCHEMBL8504553 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDPKMCES2CES1 | |
| SCHEMBL874261 | 0.72 | NPC1 (0.68) | ALDH1A1HPGDKDM4EPOLBL3MBTL1 | |
| SCHEMBL11576464 | 0.72 | NPC1 (0.51) | BCHEACHEALDH1A1HPGDL3MBTL1 | |
| SCHEMBL643368 | 0.71 | PKM (0.70) | ALDH1A1HPGDPKMKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906088-B1 | LIPOSOMAL ANTINEOPLASTON THERAPIES WITH MARKEDLY IMPROVED ANTINEOPLASTIC ACTIVITY | BURZYNSKI STANISLAW R (US) | 2005-11-23 | — | — | EP | disclosed |