Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535800 | 0.90 | ALDH1A1 (0.64) | ALDH1A1FAAHNAAAMAPTSMN1; SMN2 | |
| SCHEMBL8958534 | 0.82 | LMNA (0.51) | LMNAALDH1A1FAAHNAAAMAPT | |
| SCHEMBL9729678 | 0.81 | NPC1 (0.60) | LMNAFAAHNAAAMAPTSMN1; SMN2 | |
| SCHEMBL10622638 | 0.81 | HPGD (0.52) | LMNAALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL10617935 | 0.81 | LMNA (0.50) | LMNAALDH1A1FAAHNAAAMAPT | |
| SCHEMBL10839399 | 0.80 | NPC1 (0.62) | LMNAFAAHNAAAMAPTSMN1; SMN2 | |
| SCHEMBL6428172 | 0.79 | BCHE (0.50) | ALDH1A1KDM4EPOLBL3MBTL1GLA | |
| SCHEMBL9822446 | 0.79 | FNTA (0.49) | ALDH1A1 | |
| SCHEMBL9576428 | 0.77 | NPC1 (0.59) | LMNAFAAHNAAAMAPTSMN1; SMN2 | |
| SCHEMBL520065 | 0.76 | NPC1 (0.59) | LMNAALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325146-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 4-HYDROXY-2-PYRROLIDINONE AND N-SUBSTITUTED 4-HYDROXY-2-PYRROLIDINONES BY ENZYMATIC HYDROXYLATION | EIDGENOESSICHE TECH HOCHSCHULE (CH) | 2005-12-14 | — | — | EP | disclosed |
| US-20040009562-A1 | Process for preparing optically active 4-hydroxy-2-pyrrolidinone and n-substituted 4-hydroxy-2-pyrrolidinones by enzymatic hydroxylation | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2004-01-15 | — | — | US | disclosed |
| EP-1197561-A1 | Process for preparing optically active 4-hydroxy-2-pyrrolidinone and N-substituted 4-hydroxy-2-pyrrolidinones by enzymatic hydroxylation | Eidgenössische Technische Hochschule Zürich (CH) | 2002-04-17 | — | — | EP | disclosed |