Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17005572 | 0.86 | MAOA (0.62) | PBRM1ALDH1A1LMNAMAOAMAOB | |
| SCHEMBL16736957 | 0.80 | PBRM1 (0.52) | PBRM1CES2MAOAMAOBESR1 | |
| SCHEMBL30137886 | 0.80 | PBRM1 (1.00) | PBRM1CES2MAOAMAOBESR1 | |
| SCHEMBL28880 | 0.80 | PBRM1 (1.00) | PBRM1CES2MAOAMAOBESR1 | |
| SCHEMBL7044120 | 0.79 | DRD2 (0.53) | PBRM1ALDH1A1LMNAMAOAMAOB | |
| SCHEMBL8856533 | 0.79 | ESR1 (0.56) | PBRM1ALDH1A1LMNACES2MAOA | |
| SCHEMBL1512565 | 0.78 | MAOA (0.57) | PBRM1MAOAMAOBESR1UGT1A1 | |
| SCHEMBL2370367 | 0.77 | METAP1 (0.50) | PBRM1MAOAMAOBTDP2 | |
| SCHEMBL24773448 | 0.77 | ALDH1A1 (0.41) | PBRM1ALDH1A1LMNAMAOAMAOB | |
| SCHEMBL8756228 | 0.77 | MAOA (0.59) | PBRM1CES2MAOAMAOBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6593490-B1 | 5-Hydroxybenzocyclobutenone (meth)acrylates; pressure sensitive adhesives, protective coatings; esterification | AVERY DENNISON CORPORATION | 2003-07-15 | — | — | US | claimed |
| US-6884848-B2 | Benzocyclobutenone-functional fluoropolymers | AVERY DENNISON CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| US-6593490-B1 | 5-Hydroxybenzocyclobutenone (meth)acrylates; pressure sensitive adhesives, protective coatings; esterification | AVERY DENNISON CORPORATION | 2003-07-15 | — | — | US | disclosed |
| US-20030114551-A1 | Benzocyclobutenone-functional fluoropolymers | LI KAI (US) | 2003-06-19 | — | — | US | disclosed |
| US-6565968-B1 | Tack, peel and shear strength; performance | AVERY DENNISON CORPORATION | 2003-05-20 | — | — | US | disclosed |
| US-5869693-A | Benzocyclobutenones and polymers derived therefrom | CARLETON UNIVERSITY (CA) | 1999-02-09 | — | — | US | disclosed |