Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146119 | 1.00 | FOLH1 (0.47) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL9954035 | 1.00 | FOLH1 (0.47) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL6428434 | 1.00 | FOLH1 (0.47) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL5495877 | 1.00 | FOLH1 (0.47) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL30199558 | 0.98 | FOLH1 (0.49) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL8633803 | 0.93 | GGT1 (0.49) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL29448584 | 0.92 | MAOA (0.45) | FOLH1GGT1NOD1MAOAMAOB | |
| SCHEMBL16554492 | 0.88 | FOLH1 (0.61) | FOLH1GGT1NOD1KMT2AALOX15 | |
| Propylamine SCHEMBL28458438 | 0.88 | NOD1 (0.57) | GGT1NOD1KMT2ACPB2MEN1 | |
| SCHEMBL2254243 | 0.87 | NOD1 (0.46) | FOLH1GGT1NOD1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050152842-A1 | Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-14 | — | — | US | disclosed |
| WO-2005063304-A2 | POLY (L-GLUTAMIC ACID) PARAMAGNETIC MATERIAL COMPLEX AND USE AS A BIODEGRADABLE MRI CONTRAST AGENT | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS_SYSTEM (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050152842-A1 | Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent | TFRC, GRIA3, GLUL | FOLH1 36/4885GGT1 649/4885NOD1 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.