Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427793 | 0.90 | PRMT1 (0.55) | PRMT1SIRT1PLAUALDH1A1GAA | |
| SCHEMBL6078536 | 0.90 | PRMT1 (0.60) | PRMT1SIRT1PLAUALDH1A1GAA | |
| SCHEMBL6429753 | 0.87 | PLAU (0.60) | PLAUHSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL6428098 | 0.86 | PLAU (0.59) | PLAUHSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL6078550 | 0.86 | PRMT1 (0.68) | PRMT1SIRT1PLAUPOLBALDH1A1 | |
| SCHEMBL6428056 | 0.83 | PRMT1 (0.58) | PRMT1SIRT1PLAUIDH1ALDH1A1 | |
| SCHEMBL7520951 | 0.83 | TCF4 (0.53) | PRMT1SIRT1IDH1POLBMAPT | |
| SCHEMBL6079091 | 0.82 | PRMT1 (0.64) | PRMT1SIRT1GAA | |
| SCHEMBL6077709 | 0.82 | TCF4 (0.57) | PRMT1SIRT1PLAUIDH1POLB | |
| SCHEMBL6428060 | 0.82 | PRMT1 (0.46) | PRMT1SIRT1IDH1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181271-B1 | NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2005-01-19 | — | — | EP | claimed |