Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428056 | 0.88 | PRMT1 (0.58) | PRMT1KDM4ESIRT1ALDH1A1IDH1 | |
| SCHEMBL6428846 | 0.82 | PRMT1 (0.49) | PRMT1SIRT1ALDH1A1TSHRIDH1 | |
| SCHEMBL6427793 | 0.81 | PRMT1 (0.55) | PRMT1SIRT1ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL6078536 | 0.81 | PRMT1 (0.60) | PRMT1KDM4ESIRT1ALDH1A1TSHR | |
| SCHEMBL6079475 | 0.81 | PRMT1 (0.62) | PRMT1SIRT1HSD17B10CYP2C9MEN1 | |
| SCHEMBL7520951 | 0.80 | TCF4 (0.53) | PRMT1SIRT1CYP2C9IDH1MEN1 | |
| SCHEMBL6077709 | 0.79 | TCF4 (0.57) | PRMT1SIRT1CYP2C9IDH1MEN1 | |
| SCHEMBL6078550 | 0.77 | PRMT1 (0.68) | PRMT1SIRT1ALDH1A1TSHRMEN1 | |
| SCHEMBL6079474 | 0.77 | MEN1 (0.55) | PRMT1KDM4ESIRT1ALDH1A1HPGD | |
| SCHEMBL6079127 | 0.76 | PRMT1 (0.58) | PRMT1KDM4ESIRT1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181271-B1 | NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2005-01-19 | — | — | EP | disclosed |