Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021071 | 0.90 | DRD2 (0.68) | DRD2DRD3ITGB3ITGA2BDRD4 | |
| SCHEMBL2323421 | 0.88 | DRD2 (0.64) | DRD2DRD3ITGB3ITGA2BDRD4 | |
| SCHEMBL2744427 | 0.86 | HTR2A (0.69) | ITGB3ITGA2BDRD4L3MBTL1HTR7 | |
| SCHEMBL6700094 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BDRD4HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL9742137 | 0.84 | HTR2A (0.67) | ITGB3ITGA2BDRD4L3MBTL1HTR7 | |
| SCHEMBL7388920 | 0.84 | ALDH1A1 (0.65) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL6698553 | 0.84 | FAAH (0.54) | DRD2DRD3ITGB3ITGA2B | |
| SCHEMBL6700100 | 0.83 | ITGB3 (0.58) | ITGB3ITGA2BDRD4OPRK1HTR7 | |
| SCHEMBL6707329 | 0.82 | PRMT1 (0.67) | DRD2DRD3DRD4MEN1LMNA | |
| SCHEMBL31593043 | 0.82 | CYP2D6 (0.69) | DRD2DRD3ITGB3ITGA2BDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-10-06 | — | — | US | disclosed |
| WO-2005007625-A2 | HETEROCYCLIC AMIDES WITH ANTI-TUBERCULOSIS ACTIVITY | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | TST, KAT5, NDUFS5 | DRD2 944/4885DRD3 456/4885ITGB3 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.