Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966502 | 0.91 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AGAAPTPN5 | |
| SCHEMBL6079548 | 0.89 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6077882 | 0.84 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2AGAAPTPN5 | |
| SCHEMBL6445032 | 0.83 | LMNA (0.55) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6428098 | 0.82 | PLAU (0.59) | ALDH1A1MEN1KMT2AGAAPTPN5 | |
| SCHEMBL6078762 | 0.81 | MEN1 (0.58) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6429403 | 0.81 | LMNA (0.62) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6079433 | 0.80 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APTPN5CASP6 | |
| SCHEMBL6429753 | 0.79 | PLAU (0.60) | ALDH1A1MEN1KMT2AGAAPTPN5 | |
| SCHEMBL6077678 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AGAAPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181271-B1 | NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2005-01-19 | — | — | EP | claimed |