Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403184 | 0.80 | HCAR3 (0.40) | MAPTHCAR3MEN1KMT2ACCNA2 | |
| SCHEMBL6429943 | 0.78 | MAPT (0.39) | MAPTHCAR3MEN1KMT2ACCNA2 | |
| SCHEMBL6223839 | 0.69 | ADORA2A (0.45) | MAPTHCAR3ALDH1A1LMNA | |
| SCHEMBL6223842 | 0.69 | ADORA2A (0.45) | MAPTHCAR3ALDH1A1LMNA | |
| SCHEMBL11526154 | 0.69 | HCAR3 (0.48) | MAPTHCAR3MEN1KMT2ATDP1 | |
| SCHEMBL7885090 | 0.69 | LMNA (0.41) | MAPTHCAR3ALDH1A1POLBLMNA | |
| SCHEMBL6221396 | 0.67 | ADORA2A (0.45) | MAPTHCAR3 | |
| SCHEMBL6221401 | 0.67 | ADORA2A (0.45) | MAPTHCAR3 | |
| SCHEMBL6082397 | 0.67 | CRHR1 (0.36) | MAPTMEN1KMT2ATDP1CCNA2 | |
| SCHEMBL6082392 | 0.67 | CRHR1 (0.36) | MAPTMEN1KMT2ATDP1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |