Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429943 | 0.90 | MAPT (0.39) | HCAR3MAPTMEN1KMT2ACCNA2 | |
| SCHEMBL6429939 | 0.80 | MAPT (0.42) | HCAR3MAPTMEN1KMT2ACCNA2 | |
| SCHEMBL6223842 | 0.70 | ADORA2A (0.45) | HCAR3MAPTALDH1A1 | |
| SCHEMBL6223839 | 0.70 | ADORA2A (0.45) | HCAR3MAPTALDH1A1 | |
| SCHEMBL8568162 | 0.70 | MEN1 (0.38) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL11526154 | 0.70 | HCAR3 (0.48) | HCAR3MAPTMEN1KMT2APOLB | |
| SCHEMBL7034302 | 0.69 | IDH1 (0.38) | MAPTALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL6428301 | 0.69 | MAPT (0.35) | HCAR3MAPTMEN1KMT2APOLB | |
| SCHEMBL6221401 | 0.68 | ADORA2A (0.45) | HCAR3MAPT | |
| SCHEMBL6221396 | 0.68 | ADORA2A (0.45) | HCAR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032846-A1 | Corticotropin releasing factor antagonists | PFIZER INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032846-A1 | Corticotropin releasing factor antagonists | CRH, CRHR2, CRHR1 | HCAR3 360/4885MAPT 1457/4885MEN1 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.