Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22774382 | 0.84 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1GAAHCAR2COPS5 | |
| SCHEMBL1548244 | 0.79 | L3MBTL1 (0.37) | L3MBTL1HCAR2COPS5 | |
| SCHEMBL3159335 | 0.73 | HSD17B10 (0.37) | L3MBTL1HSD17B10SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL1548680 | 0.73 | COPS5 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1HCAR2TP53 | |
| SCHEMBL3838148 | 0.73 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL19049304 | 0.73 | POLB (0.38) | HSD17B10SMN1; SMN2POLBTP53 | |
| SCHEMBL22774740 | 0.72 | L3MBTL1 (0.57) | L3MBTL1HSD17B10SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11183274 | 0.72 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1HCAR2COPS5 | |
| SCHEMBL755522 | 0.72 | ALDH1A1 (0.44) | L3MBTL1TSHRALDH1A1HPGDTDP1 | |
| SCHEMBL1002345 | 0.72 | COPS5 (0.54) | L3MBTL1HSD17B10SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148623-A1 | Prevent reproduct of aids virus | ABBVIE INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148623-A1 | Prevent reproduct of aids virus | SERPINB1, PRSS1, SERPINA3 | L3MBTL1 1364/4885HSD17B10 594/4885SMN1; SMN2 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.