Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428445 | 0.85 | ALDH1A1 (0.47) | ALDH1A1RAB9ATSHRFEN1LMNA | |
| SCHEMBL7219663 | 0.83 | ALDH1A1 (0.45) | ALDH1A1RAB9ATYK2JAK2CYP3A4 | |
| SCHEMBL7218124 | 0.83 | TSHR (0.51) | ALDH1A1RAB9ATYK2JAK2CYP3A4 | |
| SCHEMBL6429960 | 0.80 | POLB (0.52) | ALDH1A1RAB9ATSHRLMNAGAA | |
| SCHEMBL6428937 | 0.80 | DOT1L (0.50) | ALDH1A1RAB9ATYK2JAK2CYP3A4 | |
| SCHEMBL7739128 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL27521668 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RAB9ATYK2JAK2CYP3A4 | |
| SCHEMBL103586 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TYK2JAK2CYP3A4JAK1 | |
| SCHEMBL7219666 | 0.77 | ALDH1A1 (0.38) | ALDH1A1RAB9ATYK2JAK2CYP3A4 | |
| SCHEMBL27343684 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TSHRGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100415750-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-1772749-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2006-05-17 | — | — | CN | disclosed |
| CN-1239495-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2006-02-01 | — | — | CN | disclosed |
| US-6924396-B2 | α-haloenamine reagents | PHARMACIA CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| CN-1188420-C | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1188419-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1561326-A | Alpha-haloenamine reagents | PHARMACIA CORP (US) | 2005-01-05 | — | — | CN | disclosed |
| EP-1421056-A1 | (ALPHA)-HALOENAMINE REAGENTS | Pharmacia Corporation (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040092770-A1 | Alpha-haloenamine reagents | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-6677487-B2 | COMBINING A TERTIARY AMIDE WITH A PENTAVALENT PHOSPHOROUS HALIDE IN A SOLVENT TO FORM AN ALPHA - HALOIMINIUM SALT AND CONVERTING THE ALPHA -HALOIMINIUM SALT TO THE ALPHA -HALOENAMINE WITH A BASE | PHARMACIA CORPORATION | 2004-01-13 | — | — | US | disclosed |
| CN-1221746-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-07-07 | — | — | CN | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| CN-1085221-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1994-04-13 | — | — | CN | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092770-A1 | Alpha-haloenamine reagents | HNMT, HDHD5, NISCH | ALDH1A1 373/4885RAB9A 1514/4885TYK2 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.