Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | RARG | P13631 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 6/20 | 0.49 |
| ▸ | RXRB | P28702 | 4/20 | 0.49 |
| ▸ | RXRG | P48443 | 3/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440994 | 0.84 | RARA (0.56) | RARARARBRARGRXRARXRB | |
| SCHEMBL8037417 | 0.83 | RARA (0.37) | RARARARBRARGRXRARXRB | |
| SCHEMBL11648365 | 0.82 | RARA (0.51) | RARARARBRARGRXRARXRB | |
| SCHEMBL8037038 | 0.81 | ESR2 (0.40) | RARARARBRARGRXRARXRB | |
| SCHEMBL8330612 | 0.78 | RARA (0.58) | RARARARBRARGRXRARXRB | |
| SCHEMBL3176733 | 0.77 | RXRA (0.54) | RARARARBRARGRXRARXRB | |
| SCHEMBL1616186 | 0.76 | RXRA (0.53) | RARARARBRARGRXRARXRB | |
| SCHEMBL14286073 | 0.76 | RXRA (0.53) | RARARARBRARGRXRARXRB | |
| SCHEMBL694638 | 0.76 | RXRA (0.53) | RARARARBRARGRXRARXRB | |
| SCHEMBL2095481 | 0.76 | RXRA (0.57) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567172-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC Biotech AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050101-A3 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004050101-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC BIOTECH AG (DE) | 2004-06-17 | — | — | WO | disclosed |