Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677746 | 0.78 | KCNH2 (0.39) | KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL24608079 | 0.78 | — | — | |
| SCHEMBL7802337 | 0.75 | CA1 (0.50) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3820431 | 0.73 | CA1 (0.45) | KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29428931 | 0.73 | CA1 (0.45) | KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30155037 | 0.72 | DPP4 (0.59) | KCNH2 | |
| SCHEMBL11553756 | 0.72 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2220781 | 0.72 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3784828 | 0.72 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3817668 | 0.72 | ALDH1A1 (0.46) | KCNH2KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119103-B2 | Bifunctional resorcinol, thioresorcinol, and dithioresorcinol derivative metal chelating conjugates | MALLINCKRODT LLC (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2065057-A2 | Chelating conjugates having a substituted aromatic moiety and derivatives thereof | Mallinckrodt Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065057-A2 | Chelating conjugates having a substituted aromatic moiety and derivatives thereof | Mallinckrodt Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090082324-A1 | Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates | INFACARE PHARMACEUTICAL CORPORATION | 2009-03-26 | — | — | US | disclosed |
| US-20090053137-A1 | Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof | SpecGx LLC | 2009-02-26 | — | — | US | disclosed |
| US-20090053137-A1 | Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof | SpecGx LLC | 2009-02-26 | — | — | US | disclosed |
| US-20090053137-A1 | Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof | SpecGx LLC | 2009-02-26 | — | — | US | disclosed |
| EP-1993613-A2 | CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF | Mallinckrodt, Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| EP-1988925-A2 | BIFUNCTIONAL RESORCINOL, THIORESORCINOL, AND DITHIORESORCINOL DERIVATIVE METAL CHELATING CONJUGATES | MALLINCKRODT, INC. (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007106544-A2 | CHELATING CONJUGATES HAVING A SUBSTITUTED AROMATIC MOIETY AND DERIVATIVES THEREOF | MALLINCKRODT INC. (US) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007100563-A2 | BIFUNCTIONAL RESORCINOL, THIORESORCINOL, AND DITHIORESORCINOL DERIVATIVE METAL CHELATING CONJUGATES | MALLINCKRODT INC. (US) | 2007-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053137-A1 | Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof | SLC30A5, SLC40A1, SLC46A1 | KCNH2 3102/4885KDM4E 2820/4885ALDH1A1 905/4885 |
| US-20090082324-A1 | Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates | SPR, QDPR, SLC40A1 | KCNH2 3052/4885KDM4E 3612/4885ALDH1A1 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.