SCHEMBL6432229

SCHEMBL6432229

CC(C)(C)N[Si](C)(C)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
NPC1 O15118 1/20 0.35
PLA2G1B P04054 1/20 0.35
NFKB1 P19838 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX5AP P20292 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6472439 0.87 ALDH1A1 (0.35) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL44940 0.80 ALDH1A1 (0.40) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL6435462 0.77 ALDH1A1 (0.38) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL7510367 0.75 GPR3 (0.36) MEN1KMT2A
SCHEMBL540904 0.74 GPR3 (0.35) MEN1KMT2A
Hydrochloric Acid SCHEMBL6862745 0.72 GPR3 (0.34) ALDH1A1MEN1GAAKMT2A
Hydrochloric Acid SCHEMBL995806 0.72 GPR3 (0.34) ALDH1A1MEN1GAAKMT2A
Hydrochloric Acid SCHEMBL6858048 0.72 GPR3 (0.34) ALDH1A1MEN1GAAKMT2A
SCHEMBL30885499 0.72 ALDH1A1 (0.34) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL18071854 0.71 CYP1A2 (0.35) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881493-B2 Polyolefins and uses thereof ATOFINA RESEARCH S.A. (BE) 2005-04-19 US disclosed
EP-1049741-B1 POLYOLEFIN COMPOSITIONS AND USES THEREOF TOTAL PETROCHEMICALS RES FELUY (BE) 2005-03-30 EP disclosed
US-6448349-B1 STEREORIGID METALLOCENE FOR BLOCK GAS PHASE POLYMERIZING OLEFINS HAVING THREE OR MORE CARBON ATOMS FINA RESEARCH, S.A. (BE) 2002-09-10 US disclosed
US-6348272-B1 Polyolefins and uses thereof FINA RESEARCH, S.A. (BE) 2002-02-19 US disclosed
EP-0910591-B1 SYNDIOTACTIC/ATACTIC BLOCK POLYOLEFINS, CATALYSTS AND PROCESSES FOR PRODUCING THE SAME FINA RESEARCH (BE) 2001-03-21 EP disclosed
EP-1049741-A2 POLYOLEFINS AND USES THEREOF FINA RESEARCH S.A. (BE) 2000-11-08 EP disclosed
WO-1999037711-A2 POLYOLEFINS AND USES THEREOF FINA RESEARCH S.A. (BE) 1999-07-29 WO disclosed
EP-0931814-A1 Polyolefins and uses thereof FINA RESEARCH S.A. (BE) 1999-07-28 EP disclosed
EP-0818475-A1 Syndiotactic/atactic block polyolefins, catalysts and processes for producing the same FINA RESEARCH S.A. (BE) 1998-01-14 EP disclosed