Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506396 | 0.81 | P2RX7 (0.45) | ALDH1A1P2RX7GAAL3MBTL1RAB9A | |
| SCHEMBL6394322 | 0.78 | KMT2A (0.42) | ALDH1A1P2RX7L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL6498552 | 0.78 | P2RX7 (0.46) | ALDH1A1P2RX7GAAL3MBTL1RAB9A | |
| SCHEMBL6468305 | 0.78 | P2RX7 (0.48) | ALDH1A1P2RX7GAAL3MBTL1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6389330 | 0.77 | KMT2A (0.40) | ALDH1A1P2RX7L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL6426489 | 0.74 | P2RX7 (0.43) | ALDH1A1P2RX7GAAL3MBTL1RAB9A | |
| SCHEMBL6426339 | 0.74 | LIPE (0.42) | LTA4HRAB9AMAPTP2RX3 | |
| Hydrochloric Acid SCHEMBL6427199 | 0.70 | P2RX7 (0.40) | ALDH1A1P2RX7L3MBTL1ATMMAPT | |
| SCHEMBL6388541 | 0.67 | MAPT (0.46) | ALDH1A1GAARAB9AKDM4ENSD2 | |
| SCHEMBL6427351 | 0.64 | ALDH1A1 (0.51) | ALDH1A1GAAL3MBTL1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| WO-2005075471-A2 | THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | BIOVITRUM AB (SE) | 2005-08-18 | — | — | WO | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | DGAT1 584/4885FABP3 3293/4885FABP4 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.