SCHEMBL6434034

SCHEMBL6434034

CNC(=O)c1cc(OCc2cc(O)c(O)c(O)c2)c(OCc2cc(O)c(O)c(N=O)c2)c(OCc2cc(O)c(N=O)c(N=O)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.41
BRD4 O60885 1/20 0.36
SPHK2 Q9NRA0 9/20 0.35
SPHK1 Q9NYA1 9/20 0.35
PTGES O14684 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GAA P10253 1/20 0.34
MRGPRX4 Q96LA9 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440405 0.88 LMNA (0.35) SMN1; SMN2LMNASPHK2SPHK1PTGES
SCHEMBL6440576 0.84 KDM4E (0.35) SMN1; SMN2LMNABRD4MEN1KMT2A
SCHEMBL6365561 0.72 SMN1; SMN2 (0.52) SMN1; SMN2LMNABRD4MEN1KMT2A
SCHEMBL6431280 0.72 KDM4E (0.44) SMN1; SMN2LMNAGAA
SCHEMBL16491020 0.66 LMNA (0.70) SMN1; SMN2LMNAMEN1KMT2AGAA
SCHEMBL469871 0.64 KDM4E (0.61) SMN1; SMN2LMNAGAA
SCHEMBL20392703 0.61 LMNA (0.67) SMN1; SMN2LMNAMEN1KMT2AGAA
SCHEMBL21690111 0.60 ALDH1A1 (0.69) SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL16900476 0.60 LMNA (0.61) SMN1; SMN2LMNAMEN1KMT2AGAA
SCHEMBL18027726 0.59 KCNMA1 (0.61) SMN1; SMN2LMNABRD4PTGESMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173997-B2 Laminated structure, electronic element using the same, manufacturing method therefor, electronic element array, and display unit RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-20090261320-A1 LAMINATED STRUCTURE, ELECTRONIC ELEMENT USING THE SAME, MANUFACTURING METHOD THEREFOR, ELECTRONIC ELEMENT ARRAY, AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2009-10-22 US disclosed