SCHEMBL6440405

SCHEMBL6440405

CC(=O)c1cc(OCc2cc(O)c(O)c(O)c2)c(OCc2cc(O)c(O)c(N=O)c2)c(OCc2cc(O)c(N=O)c(N=O)c2)c1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
MAOB P27338 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
TNFRSF1A P19438 1/20 0.32
TSHR P16473 1/20 0.32
SPHK2 Q9NRA0 2/20 0.31
SPHK1 Q9NYA1 2/20 0.31
HPGD P15428 1/20 0.31
PTGES O14684 1/20 0.31
MAOA P21397 1/20 0.30
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6434034 0.88 SMN1; SMN2 (0.46) LMNASMN1; SMN2SPHK2SPHK1PTGES
SCHEMBL6441897 0.88 ALOX5 (0.33) LMNAMAOBSPHK2SPHK1KDM4E
SCHEMBL6440576 0.87 KDM4E (0.35) LMNASMN1; SMN2KDM4EKMT2A
SCHEMBL12123914 0.71 CA5A (0.43) LMNASMN1; SMN2HPGDKDM4EKMT2A
SCHEMBL6430785 0.69 CA5A (0.45) LMNASMN1; SMN2HPGDKDM4EKMT2A
SCHEMBL6364664 0.69 TNFRSF1A (0.40) LMNAMAOBSMN1; SMN2TNFRSF1ATSHR
SCHEMBL2343079 0.68 MAOB (0.59) LMNAMAOBSMN1; SMN2HPGDKDM4E
SCHEMBL13846178 0.64 LMNA (0.59) LMNASMN1; SMN2TSHRKMT2A
SCHEMBL9680615 0.64 HPGD (0.58) LMNAMAOBSMN1; SMN2HPGDKDM4E
SCHEMBL13446665 0.63 TSHR (0.70) LMNASMN1; SMN2TSHRKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173997-B2 Laminated structure, electronic element using the same, manufacturing method therefor, electronic element array, and display unit RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-20090261320-A1 LAMINATED STRUCTURE, ELECTRONIC ELEMENT USING THE SAME, MANUFACTURING METHOD THEREFOR, ELECTRONIC ELEMENT ARRAY, AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2009-10-22 US disclosed