SCHEMBL6440576

SCHEMBL6440576

CC(=O)Nc1cc(OCc2cc(O)c(O)c(O)c2)c(OCc2cc(O)c(O)c(N=O)c2)c(OCc2cc(O)c(N=O)c(N=O)c2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
CYP19A1 P11511 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BRD4 O60885 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
GAA P10253 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
PPIA P62937 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440405 0.87 LMNA (0.35) KDM4ELMNAKMT2ASMN1; SMN2
SCHEMBL6434034 0.84 SMN1; SMN2 (0.46) LMNAMEN1KMT2ASMN1; SMN2BRD4
SCHEMBL6364963 0.72 LMNA (0.43) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL24728205 0.64 LMNA (0.64) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL5109701 0.60 THRB (0.53)
SCHEMBL6431265 0.60 CYP3A4 (0.46) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL5120080 0.59 THRB (0.43) MEN1KMT2AL3MBTL1GAAPTGER1
SCHEMBL30360237 0.59 TDP1 (0.67) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL28977416 0.59 TDP1 (0.67) KDM4EMAPTLMNAMEN1KMT2A
SCHEMBL3276097 0.58 PKM (0.56) KDM4EMAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173997-B2 Laminated structure, electronic element using the same, manufacturing method therefor, electronic element array, and display unit RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-20090261320-A1 LAMINATED STRUCTURE, ELECTRONIC ELEMENT USING THE SAME, MANUFACTURING METHOD THEREFOR, ELECTRONIC ELEMENT ARRAY, AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2009-10-22 US disclosed