Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | PARP1 | P09874 | 11/20 | 0.74 |
| ▸ | PIM1 | P11309 | 4/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.64 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.64 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.53 |
| ▸ | TEK | Q02763 | 2/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM4B | O94953 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898482 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL2191006 | 0.85 | PARP1 (1.00) | ALDH1A1PARP1PIM1CHEK1PDPK1 | |
| SCHEMBL29784205 | 0.85 | PARP1 (1.00) | ALDH1A1PARP1PIM1CHEK1PDPK1 | |
| SCHEMBL4870032 | 0.78 | TEK (0.69) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL1690531 | 0.78 | PARP1 (1.00) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL24819 | 0.78 | PARP1 (0.74) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL29967106 | 0.78 | PARP1 (0.74) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL391295 | 0.78 | PIM1 (0.74) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL144026 | 0.78 | PARP1 (0.74) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 | |
| SCHEMBL29440617 | 0.78 | PIM1 (0.74) | ALDH1A1PARP1PIM1CHEK1RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929660-A | Ring opening method of ethylene oxide derivative | 深圳市海滨制药有限公司 | 2022-01-14 | — | — | CN | claimed |
| EP-1885702-A2 | QUINAZOLINONES | Merck Patent GmbH (DE) | 2008-02-13 | — | — | EP | claimed |
| WO-2006125555-A2 | QUINAZOLINONES | MERCK PATENT GMBH (DE) | 2006-11-30 | — | — | WO | claimed |
| EP-1282084-B9 | METHOD FOR PREPARING PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2005-03-02 | — | — | EP | claimed |
| US-6653475-B2 | Coupling a compound with pyrimidone intermediate | J. URIACH & CIA, S.A. (ES) | 2003-11-25 | — | — | US | claimed |
| EP-1282084-B1 | METHOD FOR PREPARING PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2003-09-17 | — | — | EP | claimed |
| US-20030064986-A1 | Method for preparing pyrimidone derivatives with antifungal activity | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2003-04-03 | — | — | US | claimed |
| EP-1282084-A2 | METHOD FOR PREPARING PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | J. Uriach & Cia. S.A. (ES) | 2003-02-05 | — | — | EP | claimed |
| EP-4734979-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES | 2025-05-01 | — | — | US | disclosed |
| WO-2025006723-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| CN-117946012-A | Preparation method of nitrogen-containing heterocycle | 温州理工学院 | 2024-04-30 | — | — | CN | disclosed |
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4337662-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | Bridge Medicines (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-0566226-A1 | Quinazoline derivatives | ZENECA LIMITED (GB) | 1993-10-20 | — | — | EP | disclosed |
| EP-0520722-A1 | Therapeutic preparations containing quinazoline derivatives | ZENECA LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |
| US-4138557-A | DYE DEVELOPER | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
| US-4138263-A | Photographic silver halide material with 2-equivalent, N-heterocyclic yellow couplers | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064986-A1 | Method for preparing pyrimidone derivatives with antifungal activity | TYMP, UMPS, DPM1 | ALDH1A1 633/4885PARP1 833/4885PIM1 722/4885 |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | MLLT3, MLLT1, YEATS2 | ALDH1A1 1756/4885PARP1 811/4885PIM1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.