Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27575240 | 0.79 | KDM4E (0.53) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL6983292 | 0.75 | LMNA (0.63) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7414860 | 0.75 | TSHR (0.40) | LMNAKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28769096 | 0.74 | HSD17B10 (0.49) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7012647 | 0.73 | EGLN1 (0.44) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7020816 | 0.72 | HSP90AA1 (0.63) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7017409 | 0.72 | EGLN1 (0.53) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7016726 | 0.71 | SMN1; SMN2 (0.52) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7011986 | 0.71 | HSP90AA1 (0.51) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7015297 | 0.71 | NPC1 (0.49) | LMNAKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1561753-A2 | Benzo[b]chromenonapthyridin-7-one and pyrano[2',3':7,8]quino[2,3-b]Quinoxalin-7-one derivatives, process of synthesis, pharmaceutical compositions and their antitumoral properties for the treatment of cancer | Les Laboratoires Servier (FR) | 2005-08-10 | — | — | EP | disclosed |