Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435581 | 1.00 | LMNA (0.43) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL14724413 | 0.73 | ALDH1A1 (0.45) | LMNAKDM4EL3MBTL1HTTTRPA1 | |
| SCHEMBL6436261 | 0.72 | LMNA (0.44) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL6436267 | 0.72 | LMNA (0.44) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL11051235 | 0.72 | ALDH1A1 (0.43) | LMNAKDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL9955944 | 0.72 | ALDH1A1 (0.43) | LMNAKDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL11051238 | 0.72 | ALDH1A1 (0.43) | LMNAKDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL6547512 | 0.71 | ALDH1A1 (0.39) | LMNAKDM4EL3MBTL1HTTTRPA1 | |
| SCHEMBL22110382 | 0.69 | ALDH1A1 (0.41) | LMNAKDM4EL3MBTL1HTTALDH1A1 | |
| SCHEMBL257719 | 0.68 | ALDH1A1 (0.52) | LMNAKDM4EL3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | LMNA 4232/4885KDM4E 2413/4885L3MBTL1 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.