SCHEMBL6436046

SCHEMBL6436046

CN(C)[Al](c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.39
OPRK1 P41145 1/20 0.39
OPRL1 P41146 1/20 0.39
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
KCNN4 O15554 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 2/20 0.33
CYP2C9 P11712 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
AOC3 Q16853 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6437540 0.77 OPRM1 (0.39) OPRM1OPRK1OPRL1ALDH1A1TSHR
SCHEMBL2976898 0.71 TSHR (0.39) OPRM1OPRK1OPRL1ALDH1A1TSHR
SCHEMBL8510432 0.69 TSHR (0.37) OPRM1OPRK1OPRL1ALDH1A1TSHR
SCHEMBL8615814 0.66 RECQL (0.38) OPRM1OPRK1OPRL1ALDH1A1MAPT
SCHEMBL2968167 0.65
SCHEMBL7236327 0.64 ALDH1A1 (0.58) OPRM1OPRK1OPRL1ALDH1A1TSHR
SCHEMBL49939 0.63 ALDH1A1 (0.40) ALDH1A1TSHRMEN1KMT2AHTT
SCHEMBL8524658 0.63 ALDH1A1 (0.40) ALDH1A1TSHRMAPTAPOBEC3AAPOBEC3G
Bromide SCHEMBL15772385 0.63 TSHR (0.37) OPRM1OPRK1OPRL1ALDH1A1TSHR
Methylamine SCHEMBL9746311 0.63 LMNA (0.37) ALDH1A1TSHRMAPTCYP2C9APOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-6897176-B2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2005-05-24 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
CN-1377901-A Catalyst for olefin polymerization and process for producing olefin polymer using the same MITSUI CHEMICALS INC (JP) 2002-11-06 CN disclosed
EP-1238989-A2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst Mitsui Chemicals, Inc. (JP) 2002-09-11 EP disclosed
US-5041512-A Trialkylauminum and dialkylaluminum amide; pyrolysis; aluminum nitride; high density; fibers; ceramics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-20 US disclosed