Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427577 | 0.85 | MAPT (0.54) | KDM4EGAAMAPTPTK2BMAPK1 | |
| SCHEMBL4429989 | 0.84 | SIRT6 (0.52) | KDM4EGAAMAPTPTK2BMAPK1 | |
| Hydrochloric Acid SCHEMBL4438793 | 0.79 | MAPT (0.55) | KDM4EGAAMAPTPTK2BMAPK1 | |
| SCHEMBL6473253 | 0.79 | ALDH1A1 (0.65) | KDM4EGAAMAPTPTK2BALDH1A1 | |
| SCHEMBL6141581 | 0.74 | HTR1A (0.44) | KDM4EALDH1A1KMT2AHTR1A | |
| SCHEMBL14614703 | 0.71 | KDM4E (0.53) | KDM4EGAAMAPTPTK2BMAPK1 | |
| SCHEMBL20884918 | 0.70 | KDM4E (0.51) | KDM4EGAAMAPTPTK2BMAPK1 | |
| SCHEMBL1599761 | 0.70 | SIRT6 (0.57) | KDM4EGAAMAPTPTK2BMAPK1 | |
| SCHEMBL12073501 | 0.70 | KDM4E (0.51) | KDM4EGAAMAPTPTK2BMAPK1 | |
| SCHEMBL14922272 | 0.69 | CHKA (0.54) | KDM4EGAAMAPTPTK2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506158-A2 | DIAMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097576-A2 | DIAMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |