Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441669 | 0.76 | MAPK1 (0.40) | CACNA1GNOD2NOD1L3MBTL1KMT2A | |
| SCHEMBL19984920 | 0.76 | MTNR1A (0.47) | NOD2NOD1 | |
| SCHEMBL6443098 | 0.70 | CRBN (0.44) | CACNA1GALDH1A1IDO1 | |
| SCHEMBL6441308 | 0.70 | CRBN (0.44) | CACNA1GALDH1A1IDO1 | |
| SCHEMBL22230765 | 0.67 | CYP1A2 (0.42) | BRD4L3MBTL1KMT2AIDO1 | |
| SCHEMBL5418465 | 0.66 | ITGB3 (0.42) | ALDH1A1IDO1PLA2G10PLA2G5 | |
| SCHEMBL5026289 | 0.66 | ITGB3 (0.42) | KMT2A | |
| SCHEMBL5025707 | 0.66 | ITGB3 (0.42) | KMT2A | |
| SCHEMBL7023196 | 0.66 | NOS1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL7402874 | 0.66 | BRD4 (0.39) | NOD2NOD1BRD4MIFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |