Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 6/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863781 | 1.00 | ITGB3 (0.41) | ITGB3ITGA2BITGAVHDAC1F2 | |
| SCHEMBL31399270 | 0.81 | KEAP1 (0.44) | ITGB3ITGA2BITGAVHDAC1KEAP1 | |
| SCHEMBL30695101 | 0.78 | ITGB3 (0.51) | ITGB3ITGA2BITGAVITGB8KEAP1 | |
| SCHEMBL417814 | 0.78 | HRH3 (0.37) | ITGB3ITGA2BITGAVCYP2C9CYP2C19 | |
| SCHEMBL6948618 | 0.78 | HRH3 (0.37) | ITGB3ITGA2BITGAVCYP2C9CYP2C19 | |
| SCHEMBL29375200 | 0.78 | PSMB11 (0.46) | ITGB3ITGA2BITGAVHDAC1GHSR | |
| SCHEMBL163425 | 0.77 | MEN1 (0.41) | GAALMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2867325 | 0.77 | MEN1 (0.41) | GAALMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4410585 | 0.75 | HRH3 (0.38) | ITGB3ITGA2BITGAVHRH3GHSR | |
| SCHEMBL4402037 | 0.75 | HRH3 (0.38) | ITGB3ITGA2BITGAVHRH3GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594134-B1 | USE OF AN AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | REPUBLIC OF KOREA (MANAGEMENT: RURAL DEV ADMINISTRATION) (KR) | 2017-08-02 | — | — | EP | claimed |
| CN-103118540-B | Pesticide containing 2, 5-diketopiperazine derivative as active ingredient | Rural Development Office (KR) | 2016-02-17 | — | — | CN | claimed |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Kongju National University Industry- University Cooperation Foundation (KR) | 2013-07-25 | — | — | US | claimed |
| EP-2594134-A2 | AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Republic of Korea (Management: Rural Development Administration) (KR) | 2013-05-22 | — | — | EP | claimed |
| CN-118475351-A | Composition for inhibiting or improving cognitive function decrease | 三得利控股株式会社 | 2024-08-09 | — | — | CN | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-11382911-B2 | Plant extract containing diketopiperazine and method for producing same | SUNTORY HOLDINGS LIMITED (JP) | 2022-07-12 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| EP-2594134-B1 | USE OF AN AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | REPUBLIC OF KOREA (MANAGEMENT: RURAL DEV ADMINISTRATION) (KR) | 2017-08-02 | — | — | EP | disclosed |
| US-20170204102-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | THE REPUBLIC OF KOREA (MANAGEMENT: RURAL DEVELOPMENT ADMINISTRATION) (KR) | 2017-07-20 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| CN-103118540-B | Pesticide containing 2, 5-diketopiperazine derivative as active ingredient | Rural Development Office (KR) | 2016-02-17 | — | — | CN | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Kongju National University Industry- University Cooperation Foundation (KR) | 2013-07-25 | — | — | US | disclosed |
| EP-2594134-A2 | AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | Republic of Korea (Management: Rural Development Administration) (KR) | 2013-05-22 | — | — | EP | disclosed |
| US-20050077648-A1 | Solution casting method and polymer film | FUJIFILM CORPORATION (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204102-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | HDHD5, DAZAP1, MAPKAPK5 | ITGB3 4882/4885ITGA2B 4875/4885ITGAV 4880/4885 |
| US-20130190177-A1 | AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT | HDHD5, DAZAP1, MAPKAPK5 | ITGB3 4882/4885ITGA2B 4875/4885ITGAV 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.