SCHEMBL4402037

SCHEMBL4402037

O=C1CNC(=O)[C@H](CS)N1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.38
GHSR Q92847 1/20 0.32
ITGB3 P05106 16/20 0.32
ITGAV P06756 15/20 0.32
ITGB5 P18084 14/20 0.32
ITGA2B P08514 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12334338 1.00 HRH3 (0.38) HRH3GHSRITGB3ITGAVITGB5
SCHEMBL4410585 1.00 HRH3 (0.38) HRH3GHSRITGB3ITGAVITGB5
SCHEMBL27049693 0.80 CRBN (0.42)
SCHEMBL417814 0.80 HRH3 (0.37) HRH3GHSRITGB3ITGAVITGB5
SCHEMBL26229173 0.80 HRH3 (0.37) HRH3GHSRITGB3ITGAVITGB5
SCHEMBL31420767 0.80 HRH3 (0.37) HRH3ITGB3ITGAVITGB5ITGA2B
SCHEMBL6948618 0.80 HRH3 (0.37) HRH3GHSRITGB3ITGAVITGB5
SCHEMBL17966443 0.80 ITGB3 (0.39) HRH3ITGB3ITGAVITGB5ITGA2B
SCHEMBL10417796 0.80 ITGB3 (0.39) HRH3ITGB3ITGAVITGB5ITGA2B
SCHEMBL10417797 0.80 ITGB3 (0.39) HRH3ITGB3ITGAVITGB5ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11969002-B2 Savoury and mouthfulness taste enhancers LUCTA, S.A. (ES) 2024-04-30 US disclosed
EP-3864012-B1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS LUCTA S A (ES) 2023-09-13 EP disclosed
US-20210337850-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS LUCTA, S.A. (ES) 2021-11-04 US disclosed
EP-3864012-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS Lucta, S.A. (ES) 2021-08-18 EP disclosed
US-20150175559-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS MARQUETTE UNIVERSITY (US) 2015-06-25 US disclosed
US-20150175559-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS MARQUETTE UNIVERSITY (US) 2015-06-25 US disclosed
US-8962692-B2 Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings MARQUETTE UNIVERSITY (US) 2015-02-24 US disclosed
US-8962692-B2 Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings MARQUETTE UNIVERSITY (US) 2015-02-24 US disclosed
US-8435997-B2 Cysteine prodrugs to treat schizophrenia and drug addiction MARQUETTE UNIVERSITY (US) 2013-05-07 US disclosed
US-8435997-B2 Cysteine prodrugs to treat schizophrenia and drug addiction MARQUETTE UNIVERSITY (US) 2013-05-07 US disclosed
US-20120220596-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS UWM RESEARCH FOUNDATION, INC. (US) 2012-08-30 US disclosed
US-8173809-B2 Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings MARQUETTE UNIVERSITY (US) 2012-05-08 US disclosed
US-8173809-B2 Cysteine and cystine prodrugs to treat schizophrenia and reduce drug cravings MARQUETTE UNIVERSITY (US) 2012-05-08 US disclosed
US-20110021533-A1 CYSTEINE PRODRUGS TO TREAT SCHIZOPHRENIA AND DRUG ADDICTION MARQUETTE UNIVERSITY (US) 2011-01-27 US disclosed
US-20110021533-A1 CYSTEINE PRODRUGS TO TREAT SCHIZOPHRENIA AND DRUG ADDICTION MARQUETTE UNIVERSITY (US) 2011-01-27 US disclosed
US-7829709-B1 Cysteine prodrugs to treat schizophrenia and drug addiction MARQUETTE UNIVERSITY (US) 2010-11-09 US disclosed
US-7829709-B1 Cysteine prodrugs to treat schizophrenia and drug addiction MARQUETTE UNIVERSITY (US) 2010-11-09 US disclosed
US-20090281109-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS MARQUETTE UNIVERSITY 2009-11-12 US disclosed
US-20090281109-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS MARQUETTE UNIVERSITY 2009-11-12 US disclosed
WO-2009100431-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS MARQUETTE UNIVERSITY (US) 2009-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281109-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS CTH, SLC7A11, CBS HRH3 1934/4885GHSR 3056/4885ITGB3 4338/4885
US-20210337850-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS KCNJ6, TAS1R1, TAS2R5 HRH3 1842/4885GHSR 1507/4885ITGB3 4336/4885
US-20120220596-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS CTH, SLC7A11, CBS HRH3 1934/4885GHSR 3056/4885ITGB3 4338/4885
US-11969002-B2 Savoury and mouthfulness taste enhancers TAS1R1, KCNJ6, KCNJ5 HRH3 1800/4885GHSR 1455/4885ITGB3 4361/4885
US-20150175559-A1 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS SLC7A11, CBS, CTH HRH3 2717/4885GHSR 2179/4885ITGB3 4424/4885
US-20110021533-A1 CYSTEINE PRODRUGS TO TREAT SCHIZOPHRENIA AND DRUG ADDICTION CTH, CBS, SLC6A3 HRH3 3124/4885GHSR 3265/4885ITGB3 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.