Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319827 | 0.78 | TSHR (0.48) | THRATHRBALDH1A1TSHRMEN1 | |
| SCHEMBL10607524 | 0.76 | TSHR (0.39) | THRATHRBTSHRLMNASMN1; SMN2 | |
| SCHEMBL10607568 | 0.76 | TSHR (0.39) | THRATHRBTSHRLMNASMN1; SMN2 | |
| SCHEMBL2688149 | 0.75 | ALDH1A1 (0.62) | THRATHRBALDH1A1TSHRATM | |
| SCHEMBL10632415 | 0.73 | — | — | |
| SCHEMBL10606972 | 0.72 | THRA (0.32) | THRATHRB | |
| SCHEMBL6440253 | 0.72 | KMT2A (0.33) | ALDH1A1ATMMEN1LMNAKMT2A | |
| SCHEMBL29726739 | 0.69 | CA2 (0.60) | ALDH1A1CA2CA4TSHRMEN1 | |
| SCHEMBL9635966 | 0.69 | CA2 (0.60) | ALDH1A1CA2CA4TSHRMEN1 | |
| SCHEMBL18762038 | 0.68 | ALDH1A1 (0.54) | THRATHRBALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474719-A4 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS LLC (US) | 2005-12-14 | — | — | EP | claimed |
| US-20050090612-A1 | Polymerization process and materials for biomedical applications | ZMS, L.L.C.; A CALIFORNIA LIMITED LIABILITY CORPORATION | 2005-04-28 | — | — | US | claimed |
| EP-1474719-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2004-11-10 | — | — | EP | claimed |
| WO-2003071339-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2003-08-28 | — | — | WO | claimed |
| EP-1474719-A4 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS LLC (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050090612-A1 | Polymerization process and materials for biomedical applications | ZMS, L.L.C.; A CALIFORNIA LIMITED LIABILITY CORPORATION | 2005-04-28 | — | — | US | disclosed |
| EP-1474719-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003071339-A1 | POLYMERIZATION PROCESS AND MATERIALS FOR BIOMEDICAL APPLICATIONS | ZMS, LLC (US) | 2003-08-28 | — | — | WO | disclosed |
| US-4487904-A | Urethanized acrylic resin material for plastic lens and lens composed thereof | TORAY INDUSTRIES, INC. (JP) | 1984-12-11 | — | — | US | disclosed |