SCHEMBL10606972

SCHEMBL10606972

C=CC(=O)OC(CO)COc1c(Br)cc(Br)c(C)c1Br

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.32
THRB P10828 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10794515 0.83 THRB (0.35) THRATHRB
SCHEMBL10607568 0.79 TSHR (0.39) THRATHRB
SCHEMBL4789470 0.76 THRB (0.40) THRATHRB
SCHEMBL28089893 0.76
SCHEMBL28319485 0.75 HCAR2 (0.32)
SCHEMBL28319564 0.74 THRB (0.35) THRATHRB
SCHEMBL11048017 0.72 SMN1; SMN2 (0.40)
SCHEMBL6439716 0.72 THRA (0.35) THRATHRB
SCHEMBL18492301 0.70 HPGD (0.44)
SCHEMBL14173186 0.70 ALDH1A1 (0.47) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4812032-A DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE TORAY INDUSTRIES, INC. (JP) 1989-03-14 US disclosed
US-4721377-A COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE TORAY INDUSTRIES, INC. (JP) 1988-01-26 US disclosed
EP-0134861-B1 RESIN MATERIAL FOR PLASTIC LENS AND LENS COMPOSED THEREOF TORAY INDUSTRIES, INC. (JP) 1987-12-09 EP disclosed
EP-0176874-A2 A highly-refractive plastic lens TORAY INDUSTRIES, INC. (JP) 1986-04-09 EP disclosed
EP-0134861-A1 Resin material for plastic lens and lens composed thereof TORAY INDUSTRIES, INC. (JP) 1985-03-27 EP disclosed
US-4487904-A Urethanized acrylic resin material for plastic lens and lens composed thereof TORAY INDUSTRIES, INC. (JP) 1984-12-11 US disclosed