SCHEMBL6440647

SCHEMBL6440647

CC1(S(=O)(=O)NC(=O)Nc2nc(OC(F)(F)F)cc(OC(F)(F)F)n2)C=CC=CC1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313348 0.88 GAA (0.48) GAA
SCHEMBL8712354 0.86 GAA (0.39) GAA
SCHEMBL4047513 0.82 GAA (0.43) GAA
SCHEMBL11072808 0.80 GAA (0.31) GAA
SCHEMBL3633894 0.80 GAA (0.41) GAA
SCHEMBL11073812 0.80 GAA (0.38) GAA
SCHEMBL11076504 0.79 ALOX15 (0.33) GAA
SCHEMBL11071268 0.79 GAA (0.30) GAA
SCHEMBL3304539 0.77 GAA (0.33) GAA
SCHEMBL987339 0.77 TP53 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1536685-A1 PROCESS FOR PREPARING PASTE-EXTRUDED SULFONAMIDE COMPOSITIONS E.I. du Pont de Nemours and Company (US) 2005-06-08 EP disclosed
WO-2004023876-A1 PROCESS FOR PREPARING PASTE-EXTRUDED SULFONAMIDE COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-25 WO disclosed