Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | IAPP | P10997 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052252 | 0.82 | IAPP (0.47) | PDK2IAPPHSP90AB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7052246 | 0.82 | IAPP (0.47) | PDK2IAPPHSP90AB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10801249 | 0.76 | ALDH1A1 (0.41) | IAPPPTGS2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10801260 | 0.76 | ALDH1A1 (0.41) | IAPPPTGS2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2255346 | 0.75 | ERCC5 (0.61) | TAS1R3TAS1R1TAS1R2ERCC5FEN1 | |
| SCHEMBL10769427 | 0.74 | HSP90AB1 (0.47) | TAS1R3TAS1R1TAS1R2ERCC5FEN1 | |
| SCHEMBL27852896 | 0.73 | KMT2A (0.44) | TAS1R3TAS1R1TAS1R2ERCC5FEN1 | |
| SCHEMBL5158700 | 0.73 | RXFP1 (0.44) | TAS1R3TAS1R1TAS1R2ERCC5FEN1 | |
| SCHEMBL27635347 | 0.73 | P2RX7 (0.43) | TAS1R3TAS1R1TAS1R2ERCC5FEN1 | |
| SCHEMBL10871342 | 0.72 | L3MBTL1 (0.41) | PDK2IAPPHSP90AB1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590314-A2 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompe' S.P.A. (IT) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069782-A2 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' S.P.A. (IT) | 2004-08-19 | — | — | WO | disclosed |