Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14571997 | 0.86 | PRSS1 (0.56) | KMT2ANPC1RAB9ACES2CES1 | |
| SCHEMBL26802232 | 0.86 | NPC1 (0.56) | KMT2ANPC1RAB9ACES2CES1 | |
| SCHEMBL13890069 | 0.83 | KMT2A (0.60) | KMT2AESR1ESR2 | |
| Isophthalic Acid SCHEMBL27866970 | 0.83 | CA12 (0.54) | AKR1C3KMT2ANPC1RAB9AMITF | |
| SCHEMBL10431036 | 0.82 | AKR1C3 (0.58) | AKR1C3KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL592781 | 0.81 | RXRA (0.68) | AKR1C3KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL258461 | 0.81 | LMNA (0.68) | AKR1C3KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL29492631 | 0.81 | LMNA (0.68) | AKR1C3KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL30184304 | 0.81 | RXRA (0.68) | AKR1C3KMT2ANPC1RAB9ANR4A2 | |
| SCHEMBL26804081 | 0.81 | TAS1R3 (0.47) | KMT2ANPC1RAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238961-B1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | BAYER CHEMICALS AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6600064-B2 | Reacting dibenzyl ethers with alkylcarbonyloxybenzoic or alkoxycarbonyloxybenzoic acids in the presence of one or more acids as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
| EP-1238961-A1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | Bayer Aktiengesellschaft (DE) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, ALKBH3 | AKR1C3 445/4885KMT2A 513/4885NPC1 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.