Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL10790954 | 0.93 | TSHR (0.39) | LMNATSHRNPSR1IGF1RALOX15 | |
| SCHEMBL10345374 | 0.81 | SCN9A (0.37) | LMNATSHRNPSR1ACHEKDM4E | |
| SCHEMBL10790946 | 0.80 | SRC (0.36) | LMNATSHRNPSR1ACHEALDH1A1 | |
| SCHEMBL618870 | 0.78 | OPRM1 (0.48) | LMNATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL17602223 | 0.77 | DRD1 (0.48) | ACHEOPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL2096904 | 0.77 | DRD1 (0.48) | ACHEMAPTDRD2DRD1DRD4 | |
| SCHEMBL7620197 | 0.77 | DRD1 (0.45) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL17276390 | 0.77 | ACHE (0.46) | ACHEOPRM1OPRD1OPRK1AVPR2 | |
| Bromide SCHEMBL11452033 | 0.75 | ALDH1A1 (0.36) | LMNATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3501876 | 0.74 | ACHE (0.48) | ACHEMAPTOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855707-B2 | Method for the treatment of lipid and glucose metabolism disorders | PLIVA D.D. (HR) | 2005-02-15 | — | — | US | claimed |