SCHEMBL6442748

SCHEMBL6442748

CC(O)CN1C(C)COC1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 3/20 0.38
ALDH1A1 P00352 2/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
SLC6A3 Q01959 2/20 0.33
KCNH2 Q12809 2/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
DRD2 P14416 1/20 0.33
DRD3 P35462 1/20 0.33
HTR1A P08908 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442194 0.79 SLC18A3 (0.44) SLC18A3ALDH1A1TSHRKDM4ESLC6A3
SCHEMBL30722427 0.77 CHRM2 (0.40) ALDH1A1TSHRKDM4ESIGMAR1HPGD
SCHEMBL6444610 0.77 ALDH1A1 (0.40) SLC18A3ALDH1A1CA1CA2TSHR
SCHEMBL6440677 0.72 SLC6A3 (0.31) SLC6A3KCNH2DRD2DRD3
SCHEMBL6444637 0.72 SLC18A3 (0.41) SLC18A3ALDH1A1CA1CA2TSHR
SCHEMBL6442118 0.71 ALDH1A1 (0.50) SLC18A3ALDH1A1CA1CA2TSHR
SCHEMBL6444619 0.71 ALDH1A1 (0.41) SLC18A3ALDH1A1CA1CA2TSHR
SCHEMBL6445565 0.69 DRD2 (0.30) SLC6A3KCNH2DRD2DRD3
SCHEMBL14608922 0.68 POLB (0.44) ALDH1A1TSHRGLAHPGDPOLB
SCHEMBL6444358 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1537158-B1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF SE (DE) 2013-04-24 EP disclosed
US-20050244652-A1 Radiation curable polyurethanes with capped amino groups BASF AKTIENGESELLSCHAFT (DE) 2005-11-03 US disclosed
EP-1537158-A1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF AKTIENGESELLSCHAFT (DE) 2005-06-08 EP disclosed
WO-2004022621-A1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF AKTIENGESELLSCHAFT (DE) 2004-03-18 WO disclosed