SCHEMBL6444619

SCHEMBL6444619

CC(O)CN1CC(C)OC1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 2/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
FKBP1A P62942 1/20 0.36
KDM1A O60341 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX1 P07099 1/20 0.35
SLC18A3 Q16572 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6441137 0.79 SLC18A3 (0.41) ALDH1A1KDM4EPOLBSMN1; SMN2TSHR
SCHEMBL6445634 0.77 SIGMAR1 (0.39) ALDH1A1KDM4EPOLBSMN1; SMN2TSHR
SCHEMBL6444637 0.75 SLC18A3 (0.41) ALDH1A1KDM4EPOLBSMN1; SMN2TSHR
SCHEMBL30251939 0.74 CA1 (0.41) KDM4ECA1CA2KMT2ASLC18A3
SCHEMBL9680182 0.73 POLB (0.37) ALDH1A1KDM4EPOLBTSHRMAPK1
SCHEMBL6443019 0.72 PDK1 (0.34) ALDH1A1KDM4ESMN1; SMN2MAPK1KMT2A
SCHEMBL6442748 0.71 SLC18A3 (0.38) ALDH1A1KDM4EPOLBTSHRCA1
SCHEMBL6448012 0.69 PDK1 (0.32) ALDH1A1KDM4EMAPK1L3MBTL1
SCHEMBL6445093 0.68 PDK1 (0.32) MAPK1
SCHEMBL18978695 0.68 ABCB1 (0.38) SMN1; SMN2TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414962-B1 Oxazolidine compound NIPPON PAINT CO LTD (JP) 1994-03-16 EP claimed
EP-0414962-A1 Oxazolidine compound NIPPON PAINT CO., LTD. (JP) 1991-03-06 EP claimed
EP-1537158-B1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF SE (DE) 2013-04-24 EP disclosed
US-20050244652-A1 Radiation curable polyurethanes with capped amino groups BASF AKTIENGESELLSCHAFT (DE) 2005-11-03 US disclosed
EP-1537158-A1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF AKTIENGESELLSCHAFT (DE) 2005-06-08 EP disclosed
WO-2004022621-A1 RADIATION CURED POLYURETHANES WITH CAPPED AMINO GROUPS BASF AKTIENGESELLSCHAFT (DE) 2004-03-18 WO disclosed
US-5550246-A Calicheamicin mimics THE SCRIPPS RESEARCH INSTITUTE (US) 1996-08-27 US disclosed
WO-1996007652-A1 CALICHEAMICIN MIMICS THE SCRIPPS RESEARCH INSTITUTE (US) 1996-03-14 WO disclosed
EP-0376293-B1 Curable composition NIPPON PAINT CO LTD (JP) 1996-03-13 EP disclosed
EP-0414962-B1 Oxazolidine compound NIPPON PAINT CO LTD (JP) 1994-03-16 EP disclosed
US-5043452-A Titanium or silicon atom containing oxazolidine compound NIPPON PAINT CO., LTD. (JP) 1991-08-27 US disclosed
US-5023298-A Blend of polymer containing carboxylic anhydride, oxazolidine compound, and alkoxysilyl groups NIPPON PAINT CO., LTD. (JP) 1991-06-11 US disclosed
EP-0414962-A1 Oxazolidine compound NIPPON PAINT CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0376293-A2 Curable composition NIPPON PAINT CO., LTD. (JP) 1990-07-04 EP disclosed