Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL600629 | 0.82 | ACP3 (0.38) | MEN1ALDH1A1KMT2AGGPS1 | |
| Hydrochloric Acid SCHEMBL193696 | 0.81 | ACP3 (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL210855 | 0.80 | MEN1 (0.38) | MEN1ALDH1A1KMT2AGGPS1 | |
| SCHEMBL6030925 | 0.80 | ACP3 (0.41) | ALDH1A1 | |
| SCHEMBL1226951 | 0.78 | MEN1 (0.39) | MEN1ALDH1A1KMT2AGGPS1 | |
| Bromide SCHEMBL918125 | 0.77 | MEN1 (0.38) | MEN1ALDH1A1KMT2AGGPS1BCHE | |
| Hydrochloric Acid SCHEMBL193019 | 0.75 | BCHE (0.40) | MEN1ALDH1A1KMT2AGGPS1BCHE | |
| SCHEMBL13974630 | 0.74 | SLC6A4 (0.42) | MEN1KMT2AGGPS1 | |
| Hydrochloric Acid SCHEMBL602419 | 0.74 | SLC22A12 (0.32) | — | |
| Hydrochloric Acid SCHEMBL604178 | 0.73 | FDPS (0.33) | MEN1ALDH1A1KMT2AGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594938-A1 | ELECTROCHROMIC COMPOUNDS | Ntera Limited (IE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004067673-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2004-08-12 | — | — | WO | claimed |