Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004605 | 0.81 | ALDH1A1 (0.47) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 | |
| SCHEMBL30866391 | 0.80 | KDM4E (0.63) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 | |
| SCHEMBL9593010 | 0.78 | MAT2A (0.45) | MAPK8MAT2ACYP1A2ALDH1A1SLC6A4 | |
| SCHEMBL3475236 | 0.76 | ALDH1A1 (0.44) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 | |
| SCHEMBL30504558 | 0.76 | ALDH1A1 (0.44) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 | |
| SCHEMBL6703755 | 0.72 | KDM4E (0.62) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 | |
| SCHEMBL27630020 | 0.71 | ENPP2 (0.52) | MAT2ALMNASLC6A4DRD2ENPP2 | |
| SCHEMBL8728821 | 0.71 | TOP2A (0.39) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 | |
| SCHEMBL27291683 | 0.71 | OPRM1 (0.38) | MAT2A | |
| SCHEMBL8992827 | 0.70 | ALDH1A1 (0.42) | CYP1A2CYP2C9TOP2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080025-A1 | Macrolides | PLIVA D.D. (HR) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080025-A1 | Macrolides | IL17A, CYP51A1, IL15 | MAPK8 3784/4885MAT2A 3841/4885CYP1A2 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.