Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.52 |
| ▸ | CTSK | P43235 | 15/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444043 | 0.91 | CTSS (0.62) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6442386 | 0.90 | CTSK (0.42) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6446717 | 0.87 | CTSK (0.40) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6449675 | 0.86 | CTSK (0.39) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6446288 | 0.86 | CTSK (0.39) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6449690 | 0.83 | SMN1; SMN2 (0.45) | CTSSCTSKCTSLALOX5 | |
| SCHEMBL8617277 | 0.82 | CTSS (0.50) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6021296 | 0.82 | CTSL (0.38) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6450930 | 0.81 | CTSS (0.36) | CTSSCTSKCTSLCTSBALOX5 | |
| SCHEMBL6443383 | 0.81 | CTSS (0.51) | CTSSCTSKCTSLCTSBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |