Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680175 | 0.81 | TSHR (0.33) | POLBHRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL11329621 | 0.78 | CHRM2 (0.34) | HRH3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9617683 | 0.78 | PTGS2 (0.41) | HRH3ALDH1A1MAPK1 | |
| SCHEMBL11133602 | 0.78 | PTGS2 (0.41) | HRH3ALDH1A1MAPK1 | |
| SCHEMBL10554073 | 0.78 | PTGS2 (0.41) | HRH3ALDH1A1MAPK1 | |
| SCHEMBL6444619 | 0.73 | ALDH1A1 (0.41) | POLBALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL6441137 | 0.69 | SLC18A3 (0.41) | POLBALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL6445634 | 0.67 | SIGMAR1 (0.39) | POLBALDH1A1HPGDKDM4EHTT | |
| SCHEMBL14626847 | 0.67 | HRH3 (0.40) | POLBHRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL20226916 | 0.66 | PDK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498705-A1 | Phenol ethers derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1992-08-12 | — | — | EP | disclosed |