Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426484 | 0.81 | APAF1 (0.52) | RAD51NR1H2NR1H3MAPTALDH1A1 | |
| SCHEMBL28080842 | 0.79 | APAF1 (0.57) | RAD51NR1H2NR1H3MAPTALDH1A1 | |
| SCHEMBL6427000 | 0.78 | NR1H2 (0.60) | RAD51NR1H2NR1H3MAPTALDH1A1 | |
| SCHEMBL6431729 | 0.78 | NR1H2 (0.51) | NR1H2NR1H3MAPTALDH1A1MAPK1 | |
| SCHEMBL5049894 | 0.77 | ELANE (0.64) | MAPTALDH1A1MAPK1LMNAL3MBTL1 | |
| SCHEMBL6427989 | 0.76 | CASP1 (0.51) | NR1H2NR1H3MAPTALDH1A1MAPK1 | |
| SCHEMBL6427927 | 0.75 | MAPT (0.52) | NR1H2NR1H3MAPTALDH1A1MAPK1 | |
| SCHEMBL6428843 | 0.74 | NR1H2 (0.52) | NR1H2NR1H3MAPTALDH1A1MAPK1 | |
| SCHEMBL6466541 | 0.74 | L3MBTL1 (0.51) | NR1H2NR1H3MAPTALDH1A1MAPK1 | |
| SCHEMBL6427708 | 0.74 | NR1H2 (0.50) | NR1H2NR1H3MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |