Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.60 |
| ▸ | CTSK | P43235 | 15/20 | 0.60 |
| ▸ | CTSB | P07858 | 6/20 | 0.60 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444049 | 0.91 | CTSS (0.50) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6444054 | 0.89 | CTSS (0.50) | CTSSCTSKCTSBCTSL | |
| SCHEMBL5526272 | 0.87 | CTSS (0.67) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6575223 | 0.86 | CTSS (0.46) | CTSSCTSKCTSB | |
| SCHEMBL28395771 | 0.86 | CTSB (0.47) | CTSSCTSKCTSB | |
| SCHEMBL4367316 | 0.86 | CTSB (0.47) | CTSSCTSKCTSB | |
| SCHEMBL6818834 | 0.86 | CTSS (0.48) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6446070 | 0.86 | CTSS (0.48) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6165666 | 0.86 | CTSS (0.44) | CTSSCTSKCTSB | |
| SCHEMBL6184244 | 0.84 | CTSS (0.62) | CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |